The BIRC3 probe is located on chromosome 18 and the MALT1 probe is located on chromosome 14. A 1250 Kb probe covering the BIRC3 gene region at 11q22.2 is labeled with an orange dye. A 1280 Kb probe covering the MALT1 gene region at 18q21.31 is labeled with a green dye.
Detects t(11;18)(q21;q21) translocation in MALT lymphoma for diagnosis and treatment selection. Identifies resistance to Helicobacter pylori eradication therapy in gastric MALT lymphoma cases. Present in approximately 30% of MALT lymphomas, serving as a clonal marker for antigen-independent growth and guiding therapeutic decisions.
| Product Description | Catalog No. | Specification | Certificate | Storage |
|---|---|---|---|---|
| BIRC3/MALT1 Dual Fusion FISH Probe Kit | JLB401046-5 | 5 Tests | CE, ASR | Below 5°F (-15°C) |
| BIRC3/MALT1 Dual Fusion FISH Probe Kit | JLB401046-10 | 10 Tests | CE, ASR | Below 5°F (-15°C) |
| BIRC3/MALT1 Dual Fusion FISH Probe Kit | JLB401046-20 | 20 Tests | CE, ASR | Below 5°F (-15°C) |
