The MAFB probe is located on chromosome 20 and the IGH probe is located on chromosome 14. A 800 Kb probe covering the MAFB gene region is labeled with an orange dye, and A 1600 Kb probe covering the IGH gene region is labeled with an green dye. The MAFB gene marker region is located on 20q12 and the IGH gene marker region is located on 14q32.33, which has high specificity and will not hybridize with other chromosome centromeres to produce hybrid spots.
The translocation t(14;20) occurs in 2% of MM patients and is associated with poor prognosis.
| Product Description | Catalog No. | Specification | Certificate | Storage |
|---|---|---|---|---|
| MAFB/IGH Dual Color, Dual Fusion FISH Probe Kit | JLB401062-5 | 5 Tests | CE, ASR | Below 5°F (-15°C) |
| MAFB/IGH Dual Color, Dual Fusion FISH Probe Kit | JLB401062-10 | 10 Tests | CE, ASR | Below 5°F (-15°C) |
| MAFB/IGH Dual Color, Dual Fusion FISH Probe Kit | JLB401062-20 | 20 Tests | CE, ASR | Below 5°F (-15°C) |
