The TP53/CEN17 probe is located on chromosome 17. A 230 Kb probe covering the TP53 gene region is labeled with orange dye, and part of chromosome 17 (CEN17) is labeled with a green dye.
As a tumor suppressor gene, TP53 prevents cell division when DNA damage occurs. Deletion of TP53 at 17p13 strongly predicts resistance to purine analogues and alkylating agents, indicating poor prognosis in CLL.
| Product Description | Catalog No. | Specification | Certificate | Storage |
|---|---|---|---|---|
| TP53 FISH Probe Kit (TP53 orange probe, CEN17 green probe) | JLB401001-5 | 5 Tests | CE, ASR | Below 5°F (-15°C) |
| TP53 FISH Probe Kit (TP53 orange probe, CEN17 green probe) | JLB401001-10 | 10 Tests | CE, ASR | Below 5°F (-15°C) |
| TP53 FISH Probe Kit (TP53 orange probe, CEN17 green probe) | JLB401001-20 | 20 Tests | CE, ASR | Below 5°F (-15°C) |
